As I stood in my kitchen, the rich aroma of garlic sizzling in butter wafted through the air, pulling me into a culinary daydream. What if I combined the beloved flavors of shrimp scampi with a comfort food classic? Enter my Garlic Butter Shrimp Scampi Lasagna—an irresistible twist that marries the creamy decadence of traditional lasagna with a vibrant seafood delight. This dish not only elevates your dinner table but also offers the convenience of a make-ahead meal, tasting even better after a night in the fridge. Perfect for impressing guests or simply indulging in a cozy night in, it’s a crowd-pleaser that’s bound to become a family favorite. Ready to make some magic in your kitchen? Let’s dive into this delightful recipe!

What makes this lasagna unforgettable?
Indulgent flavors: The blend of buttery garlic shrimp and creamy cheeses creates a taste explosion that is absolutely delectable.
Ease of preparation: With straightforward steps, this recipe is perfect for home cooks of all levels, making it accessible and enjoyable.
Versatile dish: Whether it's date night or a family gathering, this lasagna is suitable for any occasion, making it a go-to tribute to comfort food.
Make-ahead convenience: Prepare it in advance for an effortless dinner that only gets better with time, saving you precious moments during busy evenings.
Crowd-pleasing appeal: Impress your guests with unique flavors that will have everyone raving, ensuring it becomes a rightful staple in your recipe repertoire.
Garlic Butter Shrimp Scampi Lasagna Ingredients
Get ready to indulge in a comforting dish!
For the Lasagna
- Lasagna noodles – 12 oz, a nice wide variety will hold up well to all those flavorful layers.
- Large shrimp – 1 lb, deveined for a succulent bite that brings the taste of the sea to your table.
- Unsalted butter – 4 tbsp, the star ingredient that lends a rich, buttery flavor to your sauce.
For the Sauce
- Garlic – 4 cloves, minced to release that wonderful aromatic essence that infuses the dish.
- Heavy cream – 1 cup, for creating a luscious and creamy texture that everyone will love.
- Grated Parmesan cheese – 1 cup, adding nutty depth that complements the shrimp beautifully.
- Italian seasoning – 2 tsp, a perfect blend to elevate the overall flavor profile of this shrimp scampi lasagna.
For the Topping
- Shredded mozzarella cheese – 2 cups, for that gooey, melty finish that adds irresistible charm to every bite.
This Garlic Butter Shrimp Scampi Lasagna is sure to become a highlight of your dinner lineup!
Step‑by‑Step Instructions for Garlic Butter Shrimp Scampi Lasagna
Step 1: Prepare the Noodles
Begin by boiling a large pot of salted water over high heat. Once the water is bubbling vigorously, add the 12 oz of lasagna noodles and cook according to the package instructions until al dente, which usually takes about 8-10 minutes. Drain the noodles and lay them flat on a towel to prevent sticking while you prepare the shrimp scampi filling.
Step 2: Sauté the Shrimp
In a large skillet, melt 2 tablespoons of unsalted butter over medium heat. Once the butter is foamy, add 4 minced cloves of garlic and sauté for about 30 seconds or until fragrant. Now, add the 1 lb of deveined shrimp to the pan and cook for 3-4 minutes until the shrimp turn pink and opaque. Remove the shrimp from the skillet and set them aside.
Step 3: Make the Cream Sauce
In the same skillet, pour in 1 cup of heavy cream and stir over medium heat until it begins to bubble gently, which should take around 2-3 minutes. Add the cooked shrimp back into the skillet along with 2 teaspoons of Italian seasoning and 1 cup of grated Parmesan cheese. Mix everything together until well combined and the cheese has melted, creating a luscious sauce.
Step 4: Layer the Lasagna
Preheat your oven to 375°F (190°C). In a 9x13 inch baking dish, spread a thin layer of the creamy shrimp mixture at the bottom. Layer with lasagna noodles, followed by more of the shrimp sauce and a sprinkle of 2 cups of shredded mozzarella cheese. Repeat these layers until all ingredients are used, finishing with a generous layer of mozzarella on top.
Step 5: Bake to Golden Perfection
Cover the assembled Garlic Butter Shrimp Scampi Lasagna with aluminum foil and place it in the preheated oven. Bake for 25 minutes, then carefully remove the foil and continue baking for another 15 minutes. Keep an eye on the lasagna as it bakes; you're looking for a delightful golden-brown top that’s bubbly and inviting.
Step 6: Cool and Serve
Once the lasagna is out of the oven, let it cool for about 10 minutes to allow the layers to set nicely. This brief resting time will help make slicing easier. When ready, cut into pieces and serve warm, savoring the irresistible combination of flavors that defines this Garlic Butter Shrimp Scampi Lasagna.

Garlic Butter Shrimp Scampi Lasagna Variations
Feel free to enhance your culinary creation with these exciting twists that will delight your taste buds!
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Gluten-Free: Use gluten-free lasagna noodles to enjoy the same delicious flavors without the wheat.
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Seafood Medley: Mix in scallops or crab along with the shrimp for a more luxurious, seafood-packed dish.
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Veggie-Loaded: Add layers of spinach, zucchini, or mushrooms to boost the nutrition and add extra texture.
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Creamy Spin: Substitute sour cream or Greek yogurt for half of the heavy cream for a tangy kick without losing richness.
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Lemon Zest: Incorporate lemon zest into the cream sauce for a bright, fresh pop that complements the shrimp beautifully.
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Spicy Kick: Mix in red pepper flakes to the garlic butter or sprinkle on top for an inviting boost of heat.
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Herb-Infused: Swap the Italian seasoning with fresh basil or dill for a fragrance-rich experience that adds freshness.
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Cheese Lover’s Delight: Experiment with a blend of different cheeses, such as ricotta or gouda, for a unique flavor profile and creamy texture.
With these variations, your Garlic Butter Shrimp Scampi Lasagna can transform into a delightful dish each time you make it!
Helpful Tricks for Garlic Butter Shrimp Scampi Lasagna
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Perfectly Cooked Shrimp: Avoid overcooking the shrimp by removing them from the pan as soon as they turn pink. They'll finish cooking in the oven.
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Prevent Sticking: To keep your lasagna noodles from sticking together, lay them flat on a towel after draining, and drizzle a little olive oil if desired.
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Layer Wisely: Start and end with a layer of sauce—this helps keep the noodles moist and prevents them from drying out during the baking process.
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Resting Time: Allow the lasagna to cool for about 10 minutes before slicing. This will make it easier to cut and serve without losing those beautiful layers.
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Make It Ahead: This Garlic Butter Shrimp Scampi Lasagna tastes even better the next day, so consider preparing it a day in advance for maximum flavor!
What to Serve with Garlic Butter Shrimp Scampi Lasagna
Elevate your mealtime experience with these delightful pairings that bring out the best in every bite!
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Garlic Bread: The classic side that perfectly complements this dish, adding a satisfying crunch and flavor that echoes the rich garlic essence.
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Caesar Salad: Crisp romaine, creamy dressing, and crunchy croutons provide a refreshing contrast to the hearty layers of lasagna and brighten up each forkful.
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Roasted Vegetables: Seasonal veggies like zucchini and bell peppers offer caramelized sweetness and a pop of color, balancing the richness of the lasagna while adding delightful texture.
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White Wine: A chilled glass of Pinot Grigio or Sauvignon Blanc elevates the meal, as the bright acidity cuts through the creaminess of the dish.
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Lemon Sorbet: This light, refreshing dessert cleanses the palate, providing a perfect finish to your meal while enhancing the seafood flavor.
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Fresh Fruit Platter: A selection of berries and citrus fruits brings a burst of color and natural sweetness, lightening the post-dinner experience and satisfying those sweet cravings.
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Homemade Tiramisu: For those seeking a decadent dessert option, the coffee-infused layers of tiramisu provide a lovely contrast to the savory lasagna, creating a delightful end to your meal.
Make Ahead Options
These Garlic Butter Shrimp Scampi Lasagna is perfect for busy weeknights, allowing you to enjoy homemade goodness with minimal hassle. You can prep the entire lasagna up to 24 hours in advance. Simply assemble the layers in your baking dish, cover tightly with plastic wrap, and refrigerate. This keeps the noodles firm and the flavors meld beautifully overnight. When you’re ready to bake, simply remove the wrap, cover with foil, and bake as instructed, adding a few extra minutes if it’s cold from the fridge. You’ll have a dish that is just as delicious with ease—perfect for impressing guests or a cozy family dinner!
How to Store and Freeze Garlic Butter Shrimp Scampi Lasagna
Fridge: Store leftovers in an airtight container for up to 3 days, preserving the flavors and keeping the lasagna moist for your next meal.
Freezer: For long-term storage, freeze the lasagna wrapped tightly in plastic wrap and then foil for up to 3 months. Thaw in the fridge overnight before reheating.
Reheating: Microwave individual portions or heat in a preheated oven at 350°F (175°C) for about 20 minutes until heated through. This Garlic Butter Shrimp Scampi Lasagna remains a delightful treat even after storage!
Serving Suggestions: When ready to serve, consider garnishing with fresh herbs like parsley or basil for added freshness and a burst of color!

Garlic Butter Shrimp Scampi Lasagna Recipe FAQs
What type of shrimp should I choose?
Absolutely! Opt for large, fresh or frozen shrimp that are deveined for the best flavor and texture. If using frozen shrimp, make sure to thaw them overnight in the refrigerator for even cooking and optimal taste.
How can I store leftovers?
Very! Store any leftover Garlic Butter Shrimp Scampi Lasagna in an airtight container in the fridge for up to 3 days. If you anticipate leftovers last longer, consider freezing them instead for later enjoyment.
Can I freeze this lasagna?
Of course! To freeze your Garlic Butter Shrimp Scampi Lasagna, wrap it tightly in plastic wrap and then again in aluminum foil to prevent freezer burn. It can be frozen for up to 3 months. When ready to enjoy, simply thaw it in the refrigerator overnight before reheating in the oven.
What should I do if my lasagna is watery?
No problem! If your lasagna turns out watery, it may be due to excess moisture in the ingredients. To fix this, make sure to drain any liquid released from the shrimp during cooking. Additionally, you can use a slotted spoon to layer out the shrimp mixture, leaving behind any excess sauce in the pan.
Is this dish safe for people with seafood allergies?
It's best to avoid this recipe altogether if there are seafood allergies present! However, you can create a variation by substituting the shrimp with grilled chicken or sautéed vegetables for a completely different yet scrumptious take on this lasagna.
How can I enhance the flavor profile?
You can absolutely elevate the flavors! Consider adding a splash of white wine to your sauce after sautéing the garlic and before adding the cream—it gives a lovely depth. Additionally, fresh herbs like parsley or basil, sprinkled on top before serving, add a vibrant touch!

Indulgent Garlic Butter Shrimp Scampi Lasagna You'll Love
Ingredients
Equipment
Method
- Prepare the Noodles: Begin by boiling a large pot of salted water over high heat. Once the water is bubbling vigorously, add the lasagna noodles and cook according to the package instructions until al dente, which usually takes about 8-10 minutes. Drain the noodles and lay them flat on a towel to prevent sticking while you prepare the shrimp scampi filling.
- Sauté the Shrimp: In a large skillet, melt 2 tablespoons of unsalted butter over medium heat. Once the butter is foamy, add 4 minced cloves of garlic and sauté for about 30 seconds or until fragrant. Now, add the deveined shrimp to the pan and cook for 3-4 minutes until the shrimp turn pink and opaque. Remove the shrimp from the skillet and set them aside.
- Make the Cream Sauce: In the same skillet, pour in the heavy cream and stir over medium heat until it begins to bubble gently, which should take around 2-3 minutes. Add the cooked shrimp back into the skillet along with the Italian seasoning and grated Parmesan cheese. Mix everything together until well combined and the cheese has melted, creating a luscious sauce.
- Layer the Lasagna: Preheat your oven to 375°F (190°C). In a 9x13 inch baking dish, spread a thin layer of the creamy shrimp mixture at the bottom. Layer with lasagna noodles, followed by more of the shrimp sauce and a sprinkle of shredded mozzarella cheese. Repeat these layers until all ingredients are used, finishing with a generous layer of mozzarella on top.
- Bake to Golden Perfection: Cover the assembled Garlic Butter Shrimp Scampi Lasagna with aluminum foil and place it in the preheated oven. Bake for 25 minutes, then carefully remove the foil and continue baking for another 15 minutes. Keep an eye on the lasagna as it bakes; you're looking for a delightful golden-brown top that’s bubbly and inviting.
- Cool and Serve: Once the lasagna is out of the oven, let it cool for about 10 minutes to allow the layers to set nicely. This brief resting time will help make slicing easier. When ready, cut into pieces and serve warm, savoring the irresistible combination of flavors that defines this Garlic Butter Shrimp Scampi Lasagna.





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